Effectivity of Uniform Multidrug Therapy on the Success of Paucibacillary and Multibacillary Leprosy Treatment

Leprosy is a chronic infectious disease caused by Mycobacterium leprae (M. leprae) that involves the integumentary and peripheral nervous system, causing neuropathy, deformity, disability. Early detection appropriate treatment are ways to break chain of transmission prevent disability in leprosy patients. The first line for standard Multidrug Therapy (MDT) regiment consisting rifampicin, dapsone, clofazimine. Standard MDT given based on classification paucibacillary (PB) multibacillary (MB). utilization has some limitations, particularly where there limited supporting test facility, difficulty determining accurately. An alternative proposed substitute Uniform-MDT (U-MDT). Several studies have been conducted use U-MDT produced promising results PB MB leprosy.